background: microbiological and chemical qualities ofmilk are among the most important issues in public health.objectives:although there are a few published studies whichhave been conducted in south east of iran this study wasperformed to investigate quality of raw milk delivered to a dairyindustry company kerman province. methods:atotal of 109raw milk samples were collected at the time of deli...

Previous work suggested that phosphorylation of DNA-PKcs at several serine/threonine (S/T) residues at positions 2609-2647 promotes DNA-PK-dependent end joining. In an attempt to clarify the role of such phosphorylation, end joining was examined in extracts of DNA-PKcs-deficient M059J cells. Joining of ends requiring gap filling prior to ligation was completely dependent on complementation of t...

Elevated expression of insulin-like growth factor-II (IGF-II) is frequently observed in a variety of human malignancies, including breast, colon, and liver cancer. As IGF-II can deliver a mitogenic signal through both IGF-IR and an alternately spliced form of the insulin receptor (IR-A), neutralizing the biological activity of this growth factor directly is a potential alternative option to IGF...

Center for Genomics and Bioinformatics, Division of Cardiovascular Epidemiology, Institute of Environmental Medicine and Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, Department of Clinical Sciences, Care of the Elderly, University of Bristol, The John James Building, Frenchay Hospital, Bristol, UK, Department of Clinical Chemistry, Karolinska Ho...

Intracellular calcium oscillations, which are oscillatory changes of cytosolic calcium concentration in response to agonist stimulation, are experimentally well observed in various living cells. Simple calcium oscillations represent the most common pattern and many mathematical models have been published to describe this type of oscillation. On the other hand, relatively few theoretical studies...

Introduction Radiation-induced bystander effect (RIBE) is a phenomenon in which radiation signals are transmitted from irradiated cells to non-irradiated ones, inducing radiation effects in these cells. RIBE plays an effective role in radiation response at environmentally relevant low doses and in radiotherapy, given its impact on adjacent normal tissues or those far from the irradiated tumor. ...

Principal applicant and corresponding author: Prof Paul KS Chan Department of Microbiology, 1/F Clinical Science Building, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China Tel: (852) 2632 2301 Fax: (852) 2647 3227 E-mail: [email protected] Formulation of a multiplex-reversetranscription-polymerase-chainreaction–based screening protocol to facilitate rapid clinical di...

We simulated the diffusion of glutamate, following the release of a single vesicle from a pre-synaptic terminal, in the synaptic cleft by using a Brownian diffusion model based on Langevin equations. The synaptic concentration time course and the time course of quantal excitatory post-synaptic current have been analyzed. The results showed that they depend on the number of receptors located at ...

A system of n asexual populations is considered where both intraand interspecific frequency-dependent game conflicts with lack of information take place. The concept of a strict n-species ESS is introduced which implies local asymptotic stability of the replicator dynamics of pure phenotypes. The dynamical concept of strict stability is also introduced which turns out to be equivalent to the st...

background organic solvents are widely used in cell biology experiments. despite increasing the solubility, they have some moderate toxic effects. therefore, selecting the appropriate solvent along with the use of suitable concentration insures the accuracy and reliability of experimental results. objectives the current study aimed to examine the cytotoxic effects of some organic solvents on va...